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Bridging epidemiology and model organisms to increase understanding of endocrine disrupting chemicals and human health effects.

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Journal of Steroid Biochemistry and Molecular Biology — Negative impact of endocrine-disrupting compounds on human reproductive health. Reproduction Fertility and Development 23 — Proceedings of the summit on environmental challenges to reproductive health and fertility: executive summary. Fertility and Sterility 89 — Exposure and effects assessment of persistent organohalogen contaminants in arctic wildlife and fish.

Science of the Total Environment — Endocrine-disrupting chemicals: an Endocrine Society scientific statement. Endocrine Reviews 30 — Effects of polychlorinated biphenyls in CD-1 mice: reproductive toxicity and intergenerational transmission. Toxicological Sciences — Darnerud PO.

Brominated flame retardants as possible endocrine disrupters. International Journal of Andrology 31 — Ovarian endocrine disruption underlies premature reproductive senescence following environmentally relevant chronic exposure to the aryl hydrocarbon receptor agonist 2,3,7,8-tetrachlorodibenzo- p -dioxin.

Biology of Reproduction 76 — Rubin BS. Bisphenol A: an endocrine disruptor with widespread exposure and multiple effects.

Endocrine Disruptors: Effects on Male and Female Reproductive Systems by Rajesh K. Naz -

Journal of Steroid Biochemistry and Molecular Biology 27 — Vinas R Watson CS. Bisphenol S disrupts estradiol-induced nongenomic signaling in a rat pituitary cell line: effects on cell functions. Environmental Health Perspectives — Hauser R Calafat AM. Phthalates and human health.

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  • Occupational and Environmental Medicine 62 — Demasculinization and feminization of male gonads by atrazine: consistent effects across vertebrate classes. Journal of Steroid Biochemistry and Molecular Biology 64 — Maternal cypermethrin exposure during lactation impairs testicular development and spermatogenesis in male mouse offspring.

    Endocrine disruption of oestrogen action and female reproductive tract cancers

    Environmental Toxicology 26 — Tiemann U. In vivo and in vitro effects of the organochlorine pesticides DDT, TCPM, methoxychlor, and lindane on the female reproductive tract of mammals: a review. Reproductive Toxicology 25 — Human fetal testis Leydig cell disruption by exposure to the pesticide dieldrin at low concentrations.

    Kavlock R Cummings A. Mode of action: inhibition of androgen receptor function—vinclozolin-induced malformations in reproductive development. Critical Reviews in Toxicology 35 — Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women.

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    New England Journal of Medicine — Modulation of steroidogenesis and estrogen signalling in the estuarine killifish Fundulus heteroclitus exposed to ethinylestradiol. Aquatic Toxicology 98 — Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat. Human Reproduction 26 — Soy, phytoestrogens and their impact on reproductive health. Molecular and Cellular Endocrinology — The effects of metals as endocrine disruptors.

    Journal of Toxicology and Environmental Health. Part B Critical Reviews 12 — Levels of environmental contaminants in human follicular fluid, serum, and seminal plasma of couples undergoing in vitro fertilization. Archives of Environmental Contamination and Toxicology 43 — The impact of endocrine disruptors on endocrine targets. Hormone and Metabolic Research 42 — Environment and women's reproductive health.

    Human Reproduction Update 17 — Sikka SC Wang R. Endocrine disruptors and estrogenic effects on male reproductive axis. Asian Journal of Andrology 10 — Reproductive Toxicology 30 — Kumar A Xagoraraki I. Pharmaceuticals, personal care products and endocrine-disrupting chemicals in U. Endocrine-disrupting chemicals and public health protection: a statement of principles from The Endocrine Society.

    Endocrinology — Hoffmann J Sommer A. Steroid hormone receptors as targets for the therapy of breast and prostate cancer — recent advances, mechanisms of resistance, and new approaches. Journal of Steroid Biochemistry and Molecular Biology 93 — De Coster S van Larebeke N. Endocrine-disrupting chemicals: associated disorders and mechanisms of action. Journal of Environmental and Public Health Characterization of steroid hormone receptor activities in hydroxylated polychlorinated biphenyls, including congeners identified in humans.

    Toxicology — Estrogenic and androgenic activity of PCBs, their chlorinated metabolites and other endocrine disruptors estimated with two in vitro yeast assays. In vitro profiling of the endocrine-disrupting potency of brominated flame retardants. Toxicological Sciences 92 — Study of natural, synthetic, and environmental chemicals for binding to the androgen receptor.

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    • Chemical Research in Toxicology 16 — In vitro study on the agonistic and antagonistic activities of bisphenol-S and other bisphenol-A congeners and derivatives via nuclear receptors. Toxicology and Applied Pharmacology — A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic.

      Screening for estrogen and androgen receptor activities in pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Life Sciences 79 — Effect of organochlorine pesticides on human androgen receptor activation in vitro. Molecular targets that link dioxin exposure to toxicity phenotypes.

      Journal of Steroid Biochemistry and Molecular Biology 96 — The aryl hydrocarbon receptor complex and the control of gene expression. Critical Reviews in Eukaryotic Gene Expression 18 — Cross-talk of dioxin and estrogen receptor signals through the ubiquitin system. Key developments in endocrine disrupter research and human health. Part B Critical Reviews 11 — Whitehead SA Rice S. Endocrine-disrupting chemicals as modulators of sex steroid synthesis.

      Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling. Reproduction — Human fetal testis: source of estrogen and target of estrogen action. Endocrine disrupter bisphenol A increases in situ estrogen production in the mouse urogenital sinus. Biology of Reproduction 84 — Atrazine-induced changes in aromatase activity in estrogen sensitive target tissues.

      Journal of Applied Toxicology 28 — Many putative endocrine disruptors inhibit prostaglandin synthesis. Environmental contaminants and human infertility: hypothesis or cause for concern? Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocrine Reviews 33 — Prenatal exposure to bisphenol a at environmentally relevant doses adversely affects the murine female reproductive tract later in life.

      Flawed experimental design reveals the need for guidelines requiring appropriate positive controls in endocrine disruption research. Endocrine disrupting chemicals and disease susceptibility. Endocrine disruption via estrogen receptors that participate in nongenomic signaling pathways. Journal of Steroid Biochemistry and Molecular Biology 44 — Non-monotonic dose effects of in utero exposure to di 2-ethylhexyl phthalate DEHP on testicular and serum testosterone and anogenital distance in male mouse fetuses.

      Effects on Male and Female Reproductive Systems, Second Edition

      Reproductive Toxicology 34 — Low-dose effects and nonmonotonic dose—responses of endocrine disrupting chemicals: has the case been made? Regulatory Toxicology and Pharmacology 64 — Darnerud PO Risberg S. Tissue localisation of tetra- and pentabromodiphenyl ether congeners BDE, and in perinatal and adult C57BL mice. Chemosphere 62 — Endocrine disrupting activity in fruits and vegetables evaluated with the E-screen assay in relation to pesticide residues.

      Exposure of the U. Environmental Health Perspectives 39 — Muncke J. Endocrine disrupting chemicals and other substances of concern in food contact materials: an updated review of exposure, effect and risk assessment. Mercea P. Physicochemical processes involved in migration of bisphenol A from polycarbonate. Journal of Applied Polymer Science — Wagner M Oehlmann J. Endocrine disruptors in bottled mineral water: estrogenic activity in the E-screen. Stark A Madar Z. Phytoestrogens: a review of recent findings.

      Use of soy protein-based formulas in infant feeding. Pediatrics — Isoflavone content of infant formulas and the metabolic fate of these phytoestrogens in early life. Early exposure to soy isoflavones and effects on reproductive health: a review of human and animal studies. Nutrients 2 — Female reproductive disorders: the roles of endocrine-disrupting compounds and developmental timing.

      Fertility and Sterility 90 — Phthalate ester toxicity in Leydig cells: developmental timing and dosage considerations. Reproductive Toxicology 23 — Barker DJ. The developmental origins of adult disease. Ben-Shlomo Y Kuh D. A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives. International Journal of Epidemiology 31 — Flame retardants in placenta and breast milk and cryptorchidism in newborn boys.

      General and Comparative Endocrinology 89 — Bruckner JV. Differences in sensitivity of children and adults to chemical toxicity: the NAS panel report.

      Endocrine System, Part 1 - Glands & Hormones: Crash Course A&P #23